Untangling structural molecular details of the endocytic adaptor protein CALM upon binding with phosphatidylinositol 4,5-bisphosphate-containing model membranes
Andreas Santamaría, Daniel Pereira, Nisha Pawar, Bernard T. Kelly, Javier Carrascosa-Tejedor, Mariana Sardo, Luís Mafra, Giovanna Fragneto, David J. Owen, Ildefonso Marín-Montesinos, Eduardo Guzmán, Nathan R. Zaccai, Armando Maestro
This study uses biophysical methods to show how CALM interacts with PtdIns(4,5)P2-containing membranes, revealing structural details of its membrane binding and curvature induction mechanism.
Communications Chemistry · Jul 29, 2025Peer-reviewedBiophysics