Combined thermodynamic and time-resolved structural analysis of interactions between AP2 and biomimetic plasma membranes provides insights into clathrin-mediated endocytosis
Armando Maestro, Nathan R. Zaccai, Juan F. Gonzalez-Martinez, Pablo Sanchez-Puga, Javier Tajuelo, Miguel A. Rubio, Andreas Santamaria, Javier Carrascosa-Tejedor, Daniel Pereira, Ildefonso Marín-Montesinos, Philipp Gutfreund, Richard Campbell, Jurij Kotar, Bernard T. Kelly, Pietro Cicuta, David J. Owen
This study uses biophysical methods to analyze AP2 interactions with biomimetic membranes, revealing insights into clathrin-mediated endocytosis mechanisms.
bioRxiv · Apr 19, 2024Biophysics