The eEF2 kinase coordinates the DNA damage response to cisplatin by supporting p53 activation
Jonathan K. M. Lim, Arash Samiei, Alberto Delaidelli, Jessica Oliveira de Santis, Vanessa Brinkmann, Christopher J. Carnie, Daniel R. Radiloff, Laura Hruby, Alisa Kahler, Jordan Cran, Gabriel Leprivier, Poul H. B. Sorensen
This study shows eEF2K is critical for the DNA damage response to cisplatin, promoting p53 activation and DNA repair depending on damage severity.
Cell Death and Disease · Jul 13, 2024Peer-reviewedMolecular Biology