JAGGED1 Stimulates Cranial Neural Crest Cell Osteoblast Commitment Pathways and Bone Regeneration Independent of Canonical NOTCH Signaling
Archana Kamalakar, Jay M. McKinney, Daniel Salinas Duron, Angélica M. Amanso, Samir A. Ballestas, Hicham Drissi, Nick J. Willett, Pallavi Bhattaram, Andrés J. Garcı́a, Levi Benjamin Wood, Steven L. Goudy
This study shows JAG1 promotes bone regeneration in mice by activating osteogenic pathways in cranial neural crest cells, independent of canonical NOTCH signaling.
Bone · Sep 25, 2020Peer-reviewedGenomics