Androgen stimulation rapidly reorganizes temporal 3D genome and epigenome states to trigger AR-mediated transcription in prostate cancer.
Elyssa M. Campbell, Geraldine Laven‐Law, Alicia M. Jones, Dayna Challis, Timothy J Peters, Grady C. Smith, Yolanda Colino‐Sanguino, David Moulder, Qian Du, Katherine A. Giles, Daniel W. Thomson, Clare Stirzaker, Theresa E. Hickey, Fátima Valdés‐Mora, Amanda Khoury, , Joanna Achinger-Kawecka
This study investigates how androgen stimulation reorganizes 3D genome and epigenome states in prostate cancer cells to activate AR-mediated transcription.
bioRxiv · Dec 17, 2024 · PreprintGenomics