Author

Amanda Khoury

Garvan Institute of Medical ResearchORCID 0000-0002-0950-7129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:ChIP-seq· 3 Research Focus:differential expression· 3 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Organism:human· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Clare StirzakeriD· 3 shared Qian DuiD· 3 shared Susan J. ClarkiD· 3 shared Catherine Elizabeth CaldoniD· 2 shared Elyssa M. CampbelliD· 2 shared Geraldine Laven‐LawiD· 2 shared Jenny Z. Song· 2 shared Joanna Achinger-KaweckaiD· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Clare StirzakerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsbioRxivPreprintDec 17, 2024

Androgen stimulation rapidly reorganizes temporal 3D genome and epigenome states to trigger AR-mediated transcription in prostate cancer.

Elyssa M. Campbell, Geraldine Laven‐Law, Alicia M. Jones…·Joanna Achinger-Kawecka

This study investigates how androgen stimulation reorganizes 3D genome and epigenome states in prostate cancer cells to activate AR-mediated transcription.

1 citation

humanChIP-seq

𝕏 PostBluesky

Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedJan 5, 2024

Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer

Joanna Achinger-Kawecka, Clare Stirzaker, Neil Portman…·Susan J. Clark

This study shows that Decitabine suppresses tumour growth in ER+ breast cancer by inducing DNA hypomethylation and altering 3D chromatin structure.

41 citationstop 3%

mouseDNA methylation

𝕏 PostBluesky

GenomicsbioRxivPreprintJan 22, 2018

Replication timing shapes the cancer epigenome and the nature of chromosomal rearrangements

Qian Du, Saul A. Bert, Nicola J. Armstrong…·Susan J. Clark

This study shows that replication timing influences epigenetic changes and chromosomal rearrangements in cancer by linking early and late replication to specific methylation and histone modifications.

2 citations

humanDNA methylation

𝕏 PostBluesky