Lipid- and protein-directed photosensitizer proximity labeling captures the cholesterol interactome
Andrew P. Becker, Elijah Biletch, John Paul Kennelly, Soon‐Gook Hong, Ashley R. Julio, Miranda Villanueva, Rohith T. Nagari, Daniel W. Turner, Nikolas R. Burton, Tomoyuki Fukuta, Liujuan Cui, Xiao Xu, Zaid Vellani, Alexander Nguyen, Julia J. Mack, , Keriann M. Backus
This paper introduces POCA, a photosensitizer-based proximity labeling method that captures both protein and lipid interactomes with high spatiotemporal resolution.
Nature Chemical Biology · Feb 6, 2026Peer-reviewedBiochemistry