Keriann M. Backus

The paper introduces POCA, a photosensitizer platform for proximity labeling of proteins, RNA, and DNA in fixed cells without genetic engineering, demonstrating its utility across multiple molecular targets.

This paper introduces GRIPs, a scalable platform for PTM editing using chimeric molecules, demonstrating functionality in multiple systems and confirming specificity through proteomics.

This paper introduces POCA, a photosensitizer-based proximity labeling method that captures both protein and lipid interactomes with high spatiotemporal resolution.

This study identifies caspase-10 inhibitors using an activation-based high-throughput screen, revealing inhibitors that preferentially target the zymogen form of caspase-10.

The paper identifies cholesterol binding to VCAM-1 as a mechanism promoting vascular inflammation by stabilizing VCAM-1 and enhancing immune cell recruitment.

This study maps chemoproteomic-detected amino acids to genomic coordinates, revealing that reactive cysteine codons are enriched for deleterious genetic variants.