Prostaglandin EP3 Receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance
Jaclyn A. Wisinski, Austin Reuter, Darby C. Peter, Michael D. Schaid, Rachel J. Fenske, Michelle E. Kimple
This study shows that EP3 receptor signaling prevents insulin hypersecretion and metabolic dysfunction in non-obese insulin-resistant mice, with unexpected effects on lean mice.
bioRxiv · Jun 14, 2019 · PreprintPhysiology