Michelle E. Kimple

This study optimizes LC-MS methods for oxylipin quantification in human plasma by using bio-inert systems and adjusting ion funnel voltages, improving signal and compound detection.

This study compares the mechanisms of FFAR4 agonist-induced insulin secretion in mouse and human islets, finding indirect effects in mice and direct effects in humans.

The paper examines Ormdl gene expression in islets from obese mice and humans, finding differential regulation and a role in beta-cell survival.

This study shows that EP3 receptor signaling prevents insulin hypersecretion and metabolic dysfunction in non-obese insulin-resistant mice, with unexpected effects on lean mice.

This study investigates how PGE2 production and EP3 receptor signaling affect human beta-cell function and compensation in different metabolic states.