Female specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and Estrogen Receptor α
Gemma Molinaro, Jacob E. Bowles, Katilynne Croom, Darya Gonzalez, Saba Mirjafary, Shari G. Birnbaum, Khaleel A. Razak, Jay R. Gibson, Kimberly M. Huber
This study identifies female-specific neocortical circuit dysfunction in a mouse model of autism linked to mGluR5 and estrogen receptor α, leading to hyperexcitability and behavioral deficits.
Cell Reports · Apr 1, 2024Peer-reviewedNeuroscience