Investigating the Effects of Psilocybin on Cognitive Flexibility in Touchscreen and Naturalistic Variations of the Probabilistic Reversal Learning Task
Dasha Anderson, Nanni Maillot, Christopher Webb Thomas, Caroline T. Golden, Gary Gilmour, Emma S J Robinson
This study examines the acute and post-acute effects of psilocybin and LSD on cognitive flexibility in rats using two probabilistic reversal learning tasks, finding no robust enhancement of reversal learning.
bioRxiv · Aug 12, 2026 · PreprintAnimal Behavior & Cognition