Extending the small molecule similarity principle to all levels of biology
Miquel Duran‐Frigola, Eduardo Pauls, Oriol Guitart-Pla, Martino Bertoni, Modesto Orozco-Ruiz, Víctor Alcalde, Víctor M. Diaz, Antonio Berenguer, David Amat, Teresa Juan-Blanco, Antonio Garcı́a de Herreros, Patrick Aloy
The paper introduces Chemical Checker, a resource that integrates bioactivity data on 800,000 small molecules and demonstrates its use in drug discovery and disease modeling.
bioRxiv · Aug 24, 2019 · PreprintBioinformatics