Antonio Garcı́a de Herreros

This study identifies HNF1B and NPHP3 mutations as causes of a new pancreatic disease, ciliogenic pancreatopathy, characterized by acinar atrophy and adipose replacement, and links ciliary dysfunction to pancreatic dysfunction in humans and mice.

The paper introduces deep neural networks to infer bioactivity signatures for uncharacterized compounds, improving activity prediction across various biological endpoints.

The paper introduces Chemical Checker, a resource that integrates bioactivity data on 800,000 small molecules and demonstrates its use in drug discovery and disease modeling.