CAR-T cells targeting CCR9 and CD1a for the treatment of T cell acute lymphoblastic leukemia
Néstor Tirado, Klaudyna Fidyt, María José Mansilla…·Pablo R. Menéndez
This paper develops and validates a dual-targeting CAR-T cell therapy for T-ALL that targets CCR9 and CD1a, showing improved efficacy and safety compared to single-targeting approaches.