Author

David E. Isenman

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Christine Chieh-Lin LaiiD· 1 shared Chun Heng Royce Lai· 1 shared Dixon NgiD· 1 shared Megha K ShahiD· 1 shared Michael J. NorrisiD· 1 shared Quynh Huong NguyeniD· 1 shared Trevor F. MoraesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Christine Chieh-Lin LaiORCID

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1 paper

Recent·Most cited

A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion.

Quynh Huong Nguyen, Chun Heng Royce Lai, Michael J. Norris, Dixon Ng, Megha K Shah, Christine Chieh-Lin Lai, David E. Isenman, Trevor F. Moraes

This paper identifies PmSLP as a bacterial surface protein that binds complement factor I to enhance immune evasion by cleaving complement components C3b and C4b without cofactors.

PLoS Pathogens · May 6, 2025Peer-reviewedMicrobiology