ImmunologybioRxivPreprint
Neutrophil-extracellular trap-associated RNA (naRNA) and LL37 enable self-amplifying inflammation in psoriasis
Franziska Herster, Zsofia Bittner, Sabine Dickhöfer…·Alexander N.R. Weber
The paper shows RNA-LL37 complexes activate neutrophils via TLR8, leading to cytokine release and NET formation, which may drive self-sustaining inflammation in psoriasis.
DOI 10.1101/324814