Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis
Vukasin M. Jovanovic, Claire Weber, Jaroslav Slamecka, Seungmi Ryu, Pei‐Hsuan Chu, Chaitali Sen, Jason M. Inman, Juliana Ferreira de Sousa, Elena S. Barnaeva, Marissa B. Hirst, David Galbraith, Pinar Ormanoglu, Yogita Jethmalani, J Colon, Sam Michael, , Ilyas Singeç
This paper develops a method to efficiently generate astrocytes from human pluripotent stem cells by bypassing neurogenesis, validated through multiple assays and adapted for drug modeling.
Stem Cell Reports · Jul 13, 2023Peer-reviewedDevelopmental Biology