Pinar Ormanoglu

Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders

This paper describes a scalable method to differentiate human pluripotent stem cells into hypothalamic arcuate neurons, which can model metabolic and reproductive disorders.

Modeling Friedreich's ataxia with Bergmann glia-enriched human cerebellar organoids

This paper develops a human cerebellar organoid model that recapitulates cerebellar development and reveals disease-specific phenotypes in Friedreich's ataxia.

Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons

This study shows that co-culturing human iPSC-derived sensory neurons with rodent satellite glia enhances their differentiation and maturation, leading to more mature phenotypes and improved disease modeling.

Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis

This paper develops a method to efficiently generate astrocytes from human pluripotent stem cells by bypassing neurogenesis, validated through multiple assays and adapted for drug modeling.

A Comprehensive Roadmap of Human Placental Development in vitro

This study develops methods to efficiently generate placental cell types from human pluripotent stem cells and validates their characteristics using multi-omics analyses.

Scalable Generation of Pseudo-Unipolar Sensory Neurons from Human Pluripotent Stem Cells

This paper describes a method to efficiently generate human sensory neurons from pluripotent stem cells for drug development.