Author

David Hoetker

University of Louisville

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

Aruni BhatnagariD· 2 shared Shahid P. BabaiD· 2 shared Ben Doeling· 1 shared Benjamin DoellingiD· 1 shared Detlef ObaliD· 1 shared Dheeraj Kumar PosaiD· 1 shared Helen I Janis· 1 shared Ibrahim JoujaiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Aruni BhatnagarORCID

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2 papers

Recent·Most cited

Carnosinylation of Cardiac Antigens Attenuates Immunogenic Responses and Improves Function in Failing Hearts

Benjamin Doelling, Mamata Chaudhari, David Hoetker, Kenneth R. Brittian, Yibing Nong, Jonah Stephan, Ibrahim Jouja, Helen I Janis, Thomas C. Mitchell, Marcin Wysoczynski, Aruni Bhatnagar, Steven Paul Jones, Shahid P. Baba

This study shows that increasing carnosine levels in failing hearts reduces aldehyde stress and immune activation, preserving cardiac function.

Journal of the American Heart Association · Jul 11, 2026Peer-reviewedImmunology

Multiomics reveals the genomic, proteomic and metabolic influences of histidyl dipeptides on heart

Keqing Yan, Zhanlong Mei, Jingjing Zhao, Md Aminul Islam Prodhan, Detlef Obal, Kartik Katragadda, Ben Doeling, David Hoetker, Dheeraj Kumar Posa, Liqing He, Xinmin Yin, Jasmit Shah, Jianmin Pan, Shesh Nath Rai, Pawel Konrad Lorkiewicz, , Shahid P. Baba

This study uses multiomics to show histidyl dipeptides regulate heart function by altering microRNAs, proteins, and metabolites involved in fatty acid oxidation and the TCA cycle.

bioRxiv · Aug 10, 2021 · PreprintSystems Biology