Programmable antigen-presenting scaffolds expand rare tumor-antigen-specific T cells from peripheral blood
Jessica Nicole DeVilla, Yoav Binenbaum, Nicoletta Cieri, David KY Zhang, Helen Ji, Vittoria Martinolli D’Arcy, Giacomo Oliveira, Michael Manos, Donna S Neuberg, Jerome Ritz, Patrick Alexander Ott, David J. Mooney, Catherine J. Wu
This paper introduces APC-ms, a platform that expands rare tumor-antigen-specific T cells from peripheral blood, achieving higher enrichment and functional properties compared to conventional methods.
bioRxiv · Oct 8, 2026 · PreprintImmunology