Yoav Binenbaum

This paper uses mathematical models to investigate T cell differentiation pathways during ex vivo expansion, finding that differentiation is dynamic and not unidirectional, with implications for improving adoptive T cell therapy.

This paper introduces APC-ms, a platform that expands rare tumor-antigen-specific T cells from peripheral blood, achieving higher enrichment and functional properties compared to conventional methods.

This study shows that matrix viscoelasticity affects dendritic cell migration and immune responses by altering actomyosin dynamics and chromatin accessibility.

This study develops a feeder-free method to generate functional human dendritic cells from pluripotent stem cells, outperforming monocyte-derived dendritic cells in antigen presentation and T cell activation.