Dysregulation of cholesterol and bile acid homeostasis in the gut-liver axis following Cryptosporidium intestinal infection
Shuhong Wang, Ai-Yu Gong, Edward Barker, David L. Williams, Christopher B. Forsyth, Liqing Yu, Xian‐Ming Chen
This study shows that Cryptosporidium infection disrupts bile acid and lipid homeostasis in the gut-liver axis, and bile supplementation reduces infection burden and restores intestinal epithelial function.
bioRxiv · Aug 1, 2024 · PreprintMicrobiology