Inflammatory Oxidative Stress Compounds Inhibit Insulin Secretion through Rapid Protein Carbonylation
Emma F. Saunders, Katherine R. Schultz, Isaiah Lowe, Aimee L. Anderson, Vrishank Bikkumalla, David Soto, Nhi Y. Tran, Sharon Baumel-Alterzon, Jefferson D. Knight, Colin T. Shearn
This study identifies protein carbonylation as a mechanism by which inflammatory oxidative stress inhibits insulin secretion in pre-type 1 diabetes.
Free Radical Biology and Medicine · Oct 31, 2025Peer-reviewedBiochemistry