David Soto

The paper characterizes synaptic proteome diversity in hippocampal trisynaptic circuits and identifies differential expression of glutamate receptor regulatory proteins.

This paper introduces a dual inhibitor targeting G9a and GSK-3β for Alzheimer's disease, showing improved memory and synaptic function in a mouse model.

This study shows that beta-hydroxybutyrate (BHB) improves AMPA receptor levels and cognitive performance in mice exposed to a high-fat diet.

This study identifies Ccnd1-Cdk4 as a regulator of GABAAR activity through phosphorylation, affecting neuronal signaling and synaptic pruning in mice.

This study shows that RTP801 regulates synaptic transmission and motor learning by modulating synaptic plasticity in the motor cortex.

The paper investigates how different stoichiometries of AMPAR-TARP complexes affect channel properties and identifies a likely functional stoichiometry in cerebellar granule cells.

This study shows that deleting the TRESK K+ channel enhances mechanical and cold sensitivity in mice, indicating its role in regulating neuronal excitability for specific sensory functions.

The paper shows homomeric Q/R edited AMPA receptors allow ion flow when desensitized, challenging the notion that desensitized channels are non-conducting.