Author

Sharon Baumel-Alterzon

City Of Hope National Medical CenterORCID 0000-0002-5283-4707Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adolfo Garcı́a-OcañaiD· 1 shared Aimee L. AndersoniD· 1 shared Alana Battad· 1 shared Colin T. ShearniD· 1 shared David Soto· 1 shared David Wesley CraigiD· 1 shared Donald K. ScottiD· 1 shared Edwin DJ Lopez Gonzalez· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMolecular Biology

Adolfo Garcı́a-OcañaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanistic Link Between Glyoxalase 1 Expression and Methylglyoxal-Induced Oncogenic Stress in Prostate Cancer

Alana Battad, Francisco Nunez, Mya Walker, Sydney Hodge, Kelani Sun, Elise Desjarlais, Edwin DJ Lopez Gonzalez, Seigmund Wai Tsuen Lai, Leanne Woods‐Burnham, Stanley E. Hooker, Rayyan Aburajab, Qianhua Feng, Min Talley, Sharon Baumel-Alterzon, David Wesley Craig, , Sarah C. Shuck

This study links elevated methylglyoxal-adducts and GLO1 genetic variants in African American/Black men with prostate cancer progression through metabolic reprogramming and impaired detoxification.

bioRxiv · Dec 9, 2025 · PreprintCancer Biology

Inflammatory Oxidative Stress Compounds Inhibit Insulin Secretion through Rapid Protein Carbonylation

Emma F. Saunders, Katherine R. Schultz, Isaiah Lowe, Aimee L. Anderson, Vrishank Bikkumalla, David Soto, Nhi Y. Tran, Sharon Baumel-Alterzon, Jefferson D. Knight, Colin T. Shearn

This study identifies protein carbonylation as a mechanism by which inflammatory oxidative stress inhibits insulin secretion in pre-type 1 diabetes.

Free Radical Biology and Medicine · Oct 31, 2025Peer-reviewedBiochemistry

NRF2 Dysregulation in Mice Leads to Inadequate Beta-Cell Mass Expansion during Pregnancy and Gestational Diabetes

Sharon Baumel-Alterzon, Isabelle Tse, Fatema Heidery, Adolfo Garcı́a-Ocaña, Donald K. Scott

This study shows that NRF2 dysregulation in mice impairs beta-cell proliferation and mass expansion during pregnancy, leading to gestational diabetes.

bioRxiv · Aug 28, 2023 · PreprintMolecular Biology