Author

David Zhou

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher Scott ColwelliD· 2 shared Cristina Antonella GhianiiD· 2 shared Huei Bin WangiD· 2 shared Adegoke A. OjewoleiD· 1 shared Adi Xiyal MukundiD· 1 shared Aly Mulji· 1 shared Amanda Mac· 1 shared Anna MatyniaiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Christopher Scott ColwellORCID

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3 papers

Recent·Most cited

Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome.

Huei Bin Wang, Natalie E Smale, Sarah H Brown, Sophia Anne Marie B Villanueva, David Zhou, Aly Mulji, Deap S Bhandal, Kyle Nguyen-Ngo, John R. Harvey, Cristina Antonella Ghiani, Christopher Scott Colwell

eLife · Sep 10, 2025Peer-reviewedNeuroscience

Long wavelength light reduces the negative consequences of dim light at night in the Cntnap2 mouse model of autism.

Huei Bin Wang, David Zhou, Shu Hon Christopher Luk, Hye In Cha, Amanda Mac, Rim Chae, Anna Matynia, Ben J. Harrison, Sina Afshari, Gene D. Block, Cristina Antonella Ghiani, Christopher Scott Colwell

This study shows that long-wavelength light reduces negative effects of dim light at night in Cntnap2 mice, improving activity rhythms and autistic behaviors.

bioRxiv · Jun 9, 2022 · PreprintNeuroscience

OSPREY 3.0: Open-Source Protein Redesign for You, with Powerful New Features

Mark A. Hallen, Jeffrey W. Martin, Adegoke A. Ojewole, Jonathan Jou, Anna U. Lowegard, Marcel S. Frenkel, Pablo Gaínza, Hunter M. Nisonoff, Adi Xiyal Mukund, Siyu Wang, Graham T. Holt, David Zhou, Elizabeth Dowd, Bruce Randall Donald

OSPREY 3.0 improves protein design software with faster algorithms, GPU support, and a Python interface, showing accurate mutation effect predictions on protein-protein binding.

Journal of Computational Chemistry · Oct 14, 2018Peer-reviewedBioinformatics