Synaptotagmin 7 outperforms synaptotagmin 1 to open and stabilize nascent fusion pores via robust membrane penetration
Kevin C. Courtney, Taraknath Mandal, Nikunj Mehta, Lanxi Wu, Yueqi Li, Debasis Das, Qiang Cui, Edwin R. Chapman
This study compares synaptotagmin-1 and synaptotagmin-7, finding that synaptotagmin-7 more effectively penetrates membranes and stabilizes fusion pores during exocytosis.
Nature Communications · Nov 27, 2023Peer-reviewedNeuroscience