Kevin C. Courtney

This study optimizes the purification of Meis1 and HoxA9 proteins and characterizes their DNA-binding and cooperative interactions.

This study shows fluorescence imaging induces phospholipid oxidation, shifting miscibility boundaries and causing membrane phase separation in model systems.

This study uses native mass spectrometry and hydrogen deuterium exchange to analyze calcium-dependent calmodulin-calmidazolium interactions, revealing ligand-induced conformational changes and binding affinity.

This paper develops a label-free, staining-based EMSA to study Pbx1 and HoxA9 DNA interactions, showing high sensitivity and quantitative results comparable to labeled methods.

This study compares synaptotagmin-1 and synaptotagmin-7, finding that synaptotagmin-7 more effectively penetrates membranes and stabilizes fusion pores during exocytosis.

This study shows that synaptotagmin-1 multimerization via the juxtamembrane linker is essential for both spontaneous and evoked neurotransmitter release.

This study investigates the role of SYT7 in synaptic function by analyzing its localization and effects on vesicle docking and synaptic plasticity in mouse hippocampal neurons.