Author

Debasish Sarkar

New York State Department of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

David LandsmaniD· 3 shared Randall H. MorseiD· 3 shared Zhengwei ZhuiD· 3 shared Elisabeth R. KnolliD· 2 shared Elizabeth R. Knoll· 1 shared Emily Paul· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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3 shared papersGenetics

David LandsmanORCID

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3 papers

Recent·Most cited

Altered Mediator dynamics during heat shock in budding yeast

Debasish Sarkar, Zhengwei Zhu, Elizabeth R. Knoll, Emily Paul, David Landsman, Randall H. Morse

The paper examines Mediator complex dynamics during heat shock in yeast, finding altered occupancy and interactions with PIC components at stress-responsive genes.

bioRxiv · Aug 25, 2020Molecular Biology

Kin28 depletion increases association of TFIID subunits Taf1 and Taf4 with promoters in Saccharomyces cerevisiae

Elisabeth R. Knoll, Zhengwei Zhu, Debasish Sarkar, David Landsman, Randall H. Morse

The paper shows that Kin28 depletion increases Taf1 and Taf4 promoter occupancy in yeast, while TBP occupancy remains unchanged, suggesting uncoupling of Taf and TBP during transcription.

Nucleic Acids Research · Mar 6, 2020Peer-reviewedGenetics

Role of the pre-initiation complex in Mediator recruitment and dynamics

Elisabeth R. Knoll, Zhengwei Zhu, Debasish Sarkar, David Landsman, Randall H. Morse

The paper investigates Mediator complex recruitment and dynamics in yeast, showing that Mediator lacking Med2-Med3-Med15 is associated with active promoters and that PIC components like TBP, Pol II, and Taf1 influence Mediator association.

eLife · Dec 12, 2018Peer-reviewedGenetics