Elisabeth R. Knoll

Kin28 depletion increases association of TFIID subunits Taf1 and Taf4 with promoters in Saccharomyces cerevisiae

The paper shows that Kin28 depletion increases Taf1 and Taf4 promoter occupancy in yeast, while TBP occupancy remains unchanged, suggesting uncoupling of Taf and TBP during transcription.

Role of the pre-initiation complex in Mediator recruitment and dynamics

The paper investigates Mediator complex recruitment and dynamics in yeast, showing that Mediator lacking Med2-Med3-Med15 is associated with active promoters and that PIC components like TBP, Pol II, and Taf1 influence Mediator association.

The Mediator co-activator complex regulates Ty1 retromobility by controlling the balance between Ty1i and Ty1 promoters

This study shows that Mediator subunits regulate Ty1 retrotransposon mobility by altering the ratio of Ty1i to Ty1 transcripts, affecting retromobility without significantly changing genomic RNA or Gag levels.