spotPCR: A Rapid and Efficient Approach for Indexing Individual Template Molecules using Unique Molecular Identifiers
Jason D. Limberis, Roland J Nagel, Soumitesh Chakravorty, Dena Block, Scott B. Dewell, Alina Nalyvayko, John Z. Metcalfe
spotPCR improves mutation detection by streamlining UMI tagging during PCR, enhancing sensitivity and specificity without requiring multiple labor-intensive steps.
bioRxiv · Dec 11, 2024 · PreprintMolecular Biology