Alina Nalyvayko

This study uses single-cell RNA sequencing to show that M. tuberculosis ESX-1 promotes the recruitment and differentiation of anti-inflammatory macrophages in infected mouse lungs.

spotPCR improves mutation detection by streamlining UMI tagging during PCR, enhancing sensitivity and specificity without requiring multiple labor-intensive steps.

The paper presents streamlined methods for generating circular DNA from the rv0678 gene to improve genotypic bedaquiline resistance testing in Mycobacterium tuberculosis.