Author

Denise Wootten

Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Brian P. CaryiD· 1 shared Giuseppe DeganuttiiD· 1 shared Marlies V. Hager· 1 shared Matthew J. BelousoffiD· 1 shared Patrick M. SextoniD· 1 shared Rylie K. Morris· 1 shared Samuel H. GellmaniD· 1 shared Zamara MariamiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPharmacology & Toxicology

Brian P. CaryORCID

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1 paper

Recent·Most cited

Prolonged signaling of backbone-modified glucagon-like peptide-1 analogues with diverse receptor trafficking

Brian P. Cary, Marlies V. Hager, Zamara Mariam, Rylie K. Morris, Matthew J. Belousoff, Giuseppe Deganutti, Patrick M. Sexton, Denise Wootten, Samuel H. Gellman

This study identifies GLP-1 analogues with prolonged signaling by modifying specific amino acids, showing how receptor trafficking and peptide structure affect signaling duration.

bioRxiv · Apr 17, 2024Pharmacology & Toxicology