Devan M. Gomez

Protracted morphine withdrawal corresponds with sex-specific alterations to motivated behavior and mesoaccumbal subcircuit dopamine cell plasticity

This study examines sex-specific changes in motivated behavior and mesoaccumbal dopamine subcircuit plasticity during protracted morphine withdrawal in mice, finding male-specific reductions in non-drug reward motivation linked to lateral DA subcircuit alterations.

Cell-type and region-specific nucleus accumbens AMPAR plasticity associated with morphine reward, reinstatement, and spontaneous withdrawal

This study investigates morphine-induced changes in glutamate transmission in nucleus accumbens neurons, identifying distinct plasticity patterns in D1- and D2-MSNs associated with reward, reinstatement, and withdrawal.

Chronic unpredictable stress promotes cell-specific plasticity in prefrontal cortex D1 and D2 pyramidal neurons

This study shows that chronic unpredictable stress causes distinct plasticity in D1 and D2 pyramidal neurons in the prefrontal cortex, affecting their excitability and synaptic transmission.