Author

Dhritiman Dey

National Institute of Pharmaceutical Education and Research

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Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Abhrajyoti GhoshiD· 1 shared Anupam GautamiD· 1 shared Bireswar Bhattacharya· 1 shared Dhrubajyoti ChattopadhyayiD· 1 shared Dipanjan GhoshiD· 1 shared Dipanjan Roy· 1 shared Dwaipayan Chaudhuri· 1 shared Kalyan GiriiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Abhrajyoti GhoshORCID

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1 paper

Recent·Most cited

A mechanistic study on the tolerance of PAM distal end mismatch by SpCas9

Dhritiman Dey, Rudra Chakravarti, Oindrila Bhattacharjee, Satyabrata Majumder, Dwaipayan Chaudhuri, Tawsif Ahmed Kazi, Dipanjan Roy, Bireswar Bhattacharya, Mansi Arya, Anupam Gautam, Rajveer Singh, Rahul Kumar Gupta, V. Ravichandiran, Dhrubajyoti Chattopadhyay, Abhrajyoti Ghosh, , Dipanjan Ghosh

The paper investigates how mismatches at the PAM distal end affect SpCas9 activity through experimental and computational methods, finding that certain mismatches reduce activity due to conformational instability.

Journal of Biological Chemistry · Jun 3, 2024Peer-reviewedGenomics