V. Ravichandiran

This study shows that dehydrozingerone prevents cognitive impairments and energy deficits caused by cranial irradiation in mice by restoring metabolic and mitochondrial functions.

This paper identifies Epoxyazadiradione as a compound that improves Parkinson's disease symptoms in mice by enhancing heat shock factor 1 and protein degradation pathways without affecting redox balance.

This study shows that KAT5 acetylates PC4 at K80 to enhance DNA repair, and this acetylation is critical for DNA damage response.

The paper investigates how mismatches at the PAM distal end affect SpCas9 activity through experimental and computational methods, finding that certain mismatches reduce activity due to conformational instability.