Author

Tawsif Ahmed Kazi

National Institute of Pharmaceutical Education and ResearchORCID 0000-0003-1663-6858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Dipanjan GhoshiD· 2 shared Dipanjan Roy· 2 shared Abhrajyoti GhoshiD· 1 shared Ankur Rao· 1 shared Anupam GautamiD· 1 shared Bireswar Bhattacharya· 1 shared Dhritiman Dey· 1 shared Dhrubajyoti ChattopadhyayiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenomics

Dipanjan GhoshORCID

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2 papers

Recent·Most cited

Genomic characterization of type I-E* CRISPR-Cas systems in Klebsiella pneumoniae: association of spacer diversity and antimicrobial resistance

Ankur Rao, Tawsif Ahmed Kazi, Sharmi Naha, Dipanjan Roy, Suchandra Mukherjee, Dipanjan Ghosh, Sulagna Basu

This study examines CRISPR-Cas systems in Klebsiella pneumoniae, finding no significant association between CRISPR-Cas and multidrug resistance, but noting diverse spacers in non-MDR strains targeting ARG-bearing plasmids.

bioRxiv · Dec 3, 2025 · PreprintGenomics

A mechanistic study on the tolerance of PAM distal end mismatch by SpCas9

Dhritiman Dey, Rudra Chakravarti, Oindrila Bhattacharjee, Satyabrata Majumder, Dwaipayan Chaudhuri, Tawsif Ahmed Kazi, Dipanjan Roy, Bireswar Bhattacharya, Mansi Arya, Anupam Gautam, Rajveer Singh, Rahul Kumar Gupta, V. Ravichandiran, Dhrubajyoti Chattopadhyay, Abhrajyoti Ghosh, , Dipanjan Ghosh

The paper investigates how mismatches at the PAM distal end affect SpCas9 activity through experimental and computational methods, finding that certain mismatches reduce activity due to conformational instability.

Journal of Biological Chemistry · Jun 3, 2024Peer-reviewedGenomics