Diverse Mechanisms of SMARCB1 Inactivation and Genome Maintenance Defects in Ultra-Rare Malignant Rhabdoid Tumors
Elizabeth Rasmussen, Elena Mironova, Zhao Lai, Kendra K. Maaß, Stefanie Volz, Dias Kurmashev, Stefan Michael Pfister, Yidong Chen, Raushan T. Kurmasheva
This study identifies diverse mechanisms of SMARCB1 inactivation and genome maintenance defects in malignant rhabdoid tumors through multi-omics profiling of patient-derived models.
bioRxiv · Mar 2, 2026 · PreprintCancer Biology