Yidong Chen

In vivo-compatible spatial multi-omics via hydrogen peroxide-independent APEX2 labeling

This paper introduces Hi-APEX, a H2O2-independent APEX2 variant for in vivo spatial multi-omics, showing improved performance in capturing redox-sensitive processes and enabling in vivo applications.

Diverse Mechanisms of SMARCB1 Inactivation and Genome Maintenance Defects in Ultra-Rare Malignant Rhabdoid Tumors

This study identifies diverse mechanisms of SMARCB1 inactivation and genome maintenance defects in malignant rhabdoid tumors through multi-omics profiling of patient-derived models.

GametesOmics: A Comprehensive Multi-Omics Database for Exploring the Gametogenesis in Humans and Mice

GametesOmics integrates multi-omics data from human and mouse gametogenesis to provide tools for analyzing gene expression, DNA methylation, and chromatin accessibility.

Sex-dependent Differences in the Genomic Profile of Lingual Sensory Neurons in Naive and Tongue-Tumor Bearing Mice

The paper identifies sex-dependent differences in transcriptomic profiles of lingual sensory neurons in naive and tongue-tumor bearing mice.

Comprehensive evaluation of ACE2 expression in female ovary by single-cell RNA-seq analysis

This study uses single-cell RNA-seq to evaluate ACE2 expression in ovarian tissues across developmental stages, identifying high ACE2 expression in PGCs and COC and its potential role in SARS-CoV-2 infection risk.