Probiotic-conditioned microbiota from preterm infants modulate immune response to pathogen challenge in a humanized mouse model
Justine Smout, Till-Robin Lesker, Lisa Hoenicke, Diego Ortiz, Mangge Zou, Friederike Kruse, Sabine M. Pirr, Maike Willers, Christoph Härtel, Christine Susanne Falk, Natalia Torow, Dorothee Viemann, Till Strowig, Jochen Huehn
This study shows that probiotic-modified microbiota from preterm infants reduces innate immune cell populations in mice and impairs bacterial clearance during infection.
Frontiers in Immunology · Apr 20, 2026Peer-reviewedImmunology