Author

Till-Robin Lesker

German Center for Infection Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Assay:proteomics· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Till StrowigiD· 2 shared Aaron E. DarlingiD· 1 shared Adrian FritziD· 1 shared Aiden HaghikiaiD· 1 shared Alexander SczyrbaiD· 1 shared Alexey A. GurevichiD· 1 shared Alice Carolyn McHardyiD· 1 shared Andreas BremgesiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Till StrowigORCID

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Author profile →

3 papers

Recent·Most cited

Probiotic-conditioned microbiota from preterm infants modulate immune response to pathogen challenge in a humanized mouse model

Justine Smout, Till-Robin Lesker, Lisa Hoenicke, Diego Ortiz, Mangge Zou, Friederike Kruse, Sabine M. Pirr, Maike Willers, Christoph Härtel, Christine Susanne Falk, Natalia Torow, Dorothee Viemann, Till Strowig, Jochen Huehn

This study shows that probiotic-modified microbiota from preterm infants reduces innate immune cell populations in mice and impairs bacterial clearance during infection.

Frontiers in Immunology · Apr 20, 2026Peer-reviewedImmunology

Gut-specific H3R signaling orchestrates microglia-dependent resolution of peripheral inflammation

Kerstin Dürholz, Leona Ehnes, Mathias Linnerbauer, Eva Schmid, Heike Danzer, Michael Hinzpeter-Schmidt, Lena Lößlein, Lena Amend, Michael Frech, Vugar Azizov, Fabian Schälter, Arne Gessner, Sébastien Lucas, Till-Robin Lesker, Regina Verena Taudte, , Mario M. Zaiss

The paper identifies gut microbiota-derived histamine as a factor enabling the CNS to suppress peripheral inflammation in RA by activating H3R in the intestine and modulating microglia.

Journal of Clinical Investigation · Jul 10, 2025Peer-reviewedImmunology

Tutorial: Assessing metagenomics software with the CAMI benchmarking toolkit

Fernando Meyer, Till-Robin Lesker, David Koslicki, Adrian Fritz, Alexey A. Gurevich, Aaron E. Darling, Alexander Sczyrba, Andreas Bremges, Alice Carolyn McHardy

This tutorial explains how to use the CAMI benchmarking toolkit to evaluate metagenomics software performance using standardized datasets and metrics.

Nature Protocols · Mar 1, 2021Peer-reviewedBioinformatics