Till Strowig

This study shows that the microbiome influences disease severity in CTLA-4 insufficient mice and humans by altering immune responses and promoting inflammation.

This study identifies IL-17A as a mediator of oxalate-induced cardiorenal injury in CKD, showing its role in inflammation and cardiac dysfunction.

This study shows that probiotic-modified microbiota from preterm infants reduces innate immune cell populations in mice and impairs bacterial clearance during infection.

This study uses ASOs to selectively inhibit mRNA translation in Prevotellaceae species, enabling functional analysis and targeted depletion in synthetic communities.

The paper shows that E. faecalis evolves to metabolize fructoselysine, reducing S. Typhimurium colonization by limiting a key nutrient.

This study shows that Prevotella intestinalis induces arthritis in resistant mice by activating intestinal immune cells and promoting Th17 differentiation through IL-6.

The paper shows that gut bacteria like Klebsiella oxytoca, under anoxic conditions, suppress Acinetobacter baumannii through metabolites from specific carbohydrates like maltose.

The paper develops MetaGEAR, a gene-centric metagenomic analysis framework, to investigate microbiome functionality in diseases and identify disease signature genes and mobile genetic elements.

The paper investigates how dietary components and Enterobacteriaceae influence competition between Prevotellaceae and Bacteroidaceae in the gut microbiota, finding that Enterobacteriaceae enhance Prevotellaceae dominance under specific conditions.

This study shows that inhibiting polysaccharide breakdown in Bacteroides thetaiotaomicron reduces cross-feeding and growth of Salmonella Typhimurium in mice.

The paper identifies gut microbiota-derived histamine as a factor enabling the CNS to suppress peripheral inflammation in RA by activating H3R in the intestine and modulating microglia.

The paper establishes a publicly available collection of 340 human gut bacterial strains, including 29 newly described species, and identifies plasmids and megaplasmids within these isolates.

This study identifies a small RNA, SrcF, essential for gut colonization of Segatella copri, regulated by complex carbohydrates and influenced by the human microbiome.

The paper compares microbiome composition and function across rheumatic diseases to identify microbial signatures predicting methotrexate response in RA and PsA.

The paper identifies a network of small RNAs that regulate sporulation in C. difficile by modulating translation of the master sporulation regulator Spo0A.

This paper shows that reducing DNA targeting activity in CRISPR systems improves genome editing efficiency in bacteria by enabling RecA-mediated repair.

This study links gut microbiota dysbiosis and altered tryptophan metabolism to increased inflammation in severe COVID-19 patients.

The paper evaluates metagenomic software tools using realistic datasets, highlighting improvements in assembly and taxon profiling while identifying remaining challenges in virus/archaea detection and reproducibility.