Function-first discovery of high affinity monoclonal antibodies using Nanovial-based plasma B cell screening
Dilip K. Challa, Joseph Michael de Rutte, Cassady Konu, Shreya Udani, Jesse Liang, Patrick J. Krohl, Ronald E. Rondon, Kent Bondensgaard, Dino Di Carlo, Jennifer Watkins-Yoon
This paper introduces Nanovials for function-first antibody discovery, enabling high-affinity antibody identification against membrane-bound targets.
bioRxiv · Aug 15, 2024 · PreprintBioengineering