Author

Patrick J. Krohl

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrei Thomas‐TikhonenkoiD· 1 shared Annette CastroiD· 1 shared Carolin Schimdt· 1 shared Cassady Konu· 1 shared Christopher Kwok· 1 shared Dan T. VogliD· 1 shared Daniel MartíneziD· 1 shared David AllmaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Andrei Thomas‐TikhonenkoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The ancestral haplotype of P2RX5 yields a B-cell surface marker and a multi-lineage immunotherapy target

Zhiwei Ang, Annette Castro, Luca Paruzzo, Carolin Schimdt, Zainul S. Hasanali, Katharina E. Hayer, Federico Stella, Samantha S. Soldan, Manuel Torres-Diz, Christopher Kwok, Patricia King Sainos, Kayla W. Ji, Patrick J. Krohl, Justyn Fine, Priyanka D. Sehgal, , Andrei Thomas‐Tikhonenko

The paper identifies P2RX5 as a new B-cell surface marker and multi-lineage immunotherapy target, showing its expression in B-cell malignancies and T-cell leukemia, and demonstrating the efficacy of P2RX5-directed therapies.

bioRxiv · Jan 26, 2026 · PreprintCancer Biology

Function-first discovery of high affinity monoclonal antibodies using Nanovial-based plasma B cell screening

Dilip K. Challa, Joseph Michael de Rutte, Cassady Konu, Shreya Udani, Jesse Liang, Patrick J. Krohl, Ronald E. Rondon, Kent Bondensgaard, Dino Di Carlo, Jennifer Watkins-Yoon

This paper introduces Nanovials for function-first antibody discovery, enabling high-affinity antibody identification against membrane-bound targets.

bioRxiv · Aug 15, 2024 · PreprintBioengineering