Regulation of checkpoint kinase signalling and tumorigenesis by the NF-κB regulated gene, CLSPN
Jill E. Hunter, Jacqueline A. Butterworth, Helene Sellier, Saimir Luli, Achilleas Floudas, Adam J. Moore, Huw D. Thomas, Kirsteen J. Campbell, Niall S. Kenneth, Robson T. Chiremba, Dina Tiniakos, Andrew M. Knight, Benjamin E. Gewurz, Fiona Oakley, Michelle D. Garrett, , Neil D. Perkins
This study shows that CLSPN, regulated by NF-κB, influences checkpoint kinase signalling and tumorigenesis, with implications for cancer treatment resistance and biomarker potential.
bioRxiv · Jun 28, 2018 · PreprintCancer Biology