Autotrophic growth of E. coli is achieved by a small number of genetic changes
Roee Ben-Nissan, Eliya Milshtein, Vanessa Pahl, Benoit de Pins, Ghil Jona, Dikla Levi, Hadas Yung, Noga Nir, Dolev Ezra, Shmuel Gleizer, Hannes Link, Εlad Noor, Ron Milo
This study identifies three genetic mutations enabling E. coli to grow autotrophically when combined with non-native enzymes for carbon fixation and energy production.
bioRxiv · Jun 3, 2023 · PreprintSynthetic Biology