Vanessa Pahl

This study quantifies the binding affinities of TRPM2 domains for ADPR analogs and shows that MHR1/2 drives activation while NUDT9H maintains structural integrity.

This paper introduces a method to simultaneously detect CRISPRi strain barcodes and metabolites using FI-MS, revealing pathway-specific metabolic changes in engineered bacteria.

This study identifies three genetic mutations enabling E. coli to grow autotrophically when combined with non-native enzymes for carbon fixation and energy production.

The paper constructs a CRISPR library of E. coli mutants to identify temperature-sensitive mutants and demonstrates their use in engineering bacterial metabolite production.