Spontaneous network activity links misrouted interneuron migration to cortical maturation abnormalities
Sathish Venkataramanappa, Jürgen Graf, Holger Haselmann, Dagmar Schütz, Oliver Storch, Dominic Roemer, Praveen Ashok Kumar, Nelli Blank-Stein, Christian Mayer, Knut Holthoff, Knut Kirmse, Philipp Abe, Ralf K. Stumm
This study shows that disrupted migration of inhibitory neurons leads to persistent functional deficits in cortical networks, linking migratory guidance to circuit integrity.
bioRxiv · May 8, 2026 · PreprintNeuroscience