Author

Dominique Bétemps

Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:protein structure· 1

Frequent Co-Authors

Jérémy Verchère· 2 shared Thierry BaroniD· 2 shared Anna SalvettiiD· 1 shared Charly MayraniD· 1 shared Daisy BougardiD· 1 shared Damien Gaillard· 1 shared Dorian Sargent· 1 shared Jean-Noël ArsaciD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Jérémy Verchère

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2 papers

Recent·Most cited

Seeded propagation of alpha-synuclein aggregation in mouse brain using protein misfolding cyclic amplification

Simon Nicot, Jérémy Verchère, Maxime Bélondrade, Charly Mayran, Dominique Bétemps, Daisy Bougard, Thierry Baron

This study uses PMCA to show that alpha-synuclein aggregates from mutant mice can seed aggregation in wild-type mice and other substrates, mimicking prion-like behavior.

bioRxiv · Jan 26, 2019 · PreprintNeuroscience

Investigating the neuroprotective effect of AAV-mediated β-synuclein overexpression in a transgenic model of synucleinopathy

Dorian Sargent, Dominique Bétemps, Matthieu Drouyer, Jérémy Verchère, Damien Gaillard, Jean-Noël Arsac, Latifa Lakhdar, Anna Salvetti, Thierry Baron

This study investigates whether β-synuclein overexpression via AAV can inhibit α-synuclein aggregation in a synucleinopathy model, but finds no delay in disease onset and reports specific β-synuclein aggregates in treated mice.

Scientific Reports · Nov 27, 2018Peer-reviewedNeuroscience